Domestic Water Buffalo is not threatened or listed on CITES. The Asian Buffalo, Bubalus bubalis, has been heavily domesticated and is therefore now widespread. Their native area was from Central India in the south of Nepal in the west, to Vietnam and Malaysia in the east.
In general, bovine horns are effective deterrents against predators. Tigers are the only other predator for Buffaloes. Humans have been a significant threat to Buffalo, both through hunting and habitat invasion and fragmentation. In contrast, the wild species - Bubalus arnee - is in danger and its native population is less than 4.000 individuals in the wild.