The population of this species remains widespread in Africa, totaling 25 to 45 thousand individuals, but tends to decrease due to loss of habitat and persecution by humans, for competing with domestic cattle. The African Wildlife Foundation (AWF) mitigates the conflict between humans and wildlife, building livestock sites, protecting their property from predators such as Hyenas. The Botswana Predator Conservation Trust (BPCT) directs research and education efforts to preserve Africa's great predators and their habitats, in which the Spotted Hyena is included.
In the savannas, Hyenas and lions compete directly for food, often leading to antagonistic encounters that can result in death.